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Because it's a shorter, unmodified fragment, Sermorelin has a very short half-life in the body, often just a matter of minutes

In 1C metabolism, the metabolites dTMP and 10-formyl-THF are critical for de novo synthesis of pyrimidines and purines [81]

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Instead, the basic group causing the unusual acidity of the thiol group resides in the glutathione molecule itself in the form of the free -carboxylate of the glutamyl residue (Gustafsson et al., 2001)